Multiscale Mechanical Modeling of Skeletal Muscle: A Systemic Review of the Literature - Ecole Nationale du Génie de l'Eau et de l'Environnement de Strasbourg Accéder directement au contenu
Article Dans Une Revue Journal of Medical and Biological Engineering Année : 2024

Multiscale Mechanical Modeling of Skeletal Muscle: A Systemic Review of the Literature

Résumé

Abstract Purpose From the myofibrils to the whole muscle scale, muscle micro-constituents exhibit passive and active mechanical properties, potentially coupled to electrical, chemical, and thermal properties. Experimental characterization of some of these properties is currently not available for all muscle constituents. Multiscale multiphysics models have recently gained interest as a numerical alternative to investigate the healthy and diseased physiological behavior of the skeletal muscle. Methods This paper refers to the multiscale mechanical models proposed in the literature to investigate the mechanical properties and behavior of skeletal muscles. More specifically, we focus on the scale transition methods, constitutive laws and experimental data implemented in these models. Results Using scale transition methods such as homogenization, coupled to appropriate constitutive behavior of the constituents, these models explore the mechanisms of ageing, myopathies, sportive injuries, and muscle contraction. Conclusion Emerging trends include the development of multiphysics simulations and the coupling of modeling with the acquisition of experimental data at different scales, with increasing focus to little known constituents such as the extracellular matrix and the protein titin.
Fichier principal
Vignette du fichier
240503_Multiscale_mechanical_muscle_models_review_V6 Accepted.pdf (856.24 Ko) Télécharger le fichier
Origine Fichiers produits par l'(les) auteur(s)

Dates et versions

hal-04621020 , version 1 (22-06-2024)

Identifiants

Citer

Aude Loumeaud, Philippe Pouletaut, Sabine Bensamoun, Daniel George, Simon Chatelin. Multiscale Mechanical Modeling of Skeletal Muscle: A Systemic Review of the Literature. Journal of Medical and Biological Engineering, 2024, ⟨10.1007/s40846-024-00879-3⟩. ⟨hal-04621020⟩
0 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Mastodon Facebook X LinkedIn More